CHEMICAL AND PHARMACOLOGICAL EVOLUTION OF SOME SYNTHESIZED CHALCONES AND HETROCYCLIC COMPOUNDS

Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose medicinal products. With centuries had emerged as a magnanimous field science getting facelift from available natural compounds synthesis newer complex molecules possessing activity while transit earth synthetically furnished laboratory. Medicinal or pharmaceutical discipline at intersection pharmacology involved with designing, synthesizing developing drugs. Chalconesis generic term given bearing 1,3-diarylprop2-en-1-one, which can be functionlized in propane chain by presence olefinic, keto and/or hydroxyl group. Chalcones belongs flavonoid family. Chemically chalcones consisted open flavonoids two aromaticrings are joined three carbon a,ß-unsaturated carbonyl system (Dhar, 1981). Microorganisms heterogeneous group several distinct classes living beings. They were classified under third kingdom, theProstita. Based differences cellular organization biochemistry, kingdom prostita has been divided into groups, Prokaryotes Eukaryotes. Bacteria blue green algae prokaryotes fungi, other algae, slime moulds protozoa eukaryotes. Anti-fungal drugs among most frequently prescribed preparations because their fungal activity. widely used treatment diseases such Candidiasis Apergillosis. These agents prevent infection. Anti-oxidant Oxidation.